Pasquale Maffia Selected Research

Apolipoproteins E (ApoE)

8/2020	Modulating Lipoprotein Transcellular Transport and Atherosclerotic Plaque Formation in ApoE-/- Mice via Nanoformulated Lipid-Methotrexate Conjugates.
1/2018	'Blow my mind(in)' - mindin neutralization for the prevention of atherosclerosis?
1/2018	Immune cell census in murine atherosclerosis: cytometry by time of flight illuminates vascular myeloid cell diversity.
1/2016	Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in Aged ApoE-/- Mice.
6/2015	Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors.
1/2014	Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation.
12/2009	The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice.

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Pasquale Maffia Research Topics

Disease

19	Inflammation (Inflammations) 05/2024 - 07/2003
12	Atherosclerosis 04/2024 - 11/2012
11	Hypertension (High Blood Pressure) 05/2024 - 01/2018
6	Neointima 01/2014 - 02/2002
6	Vascular System Injuries 01/2012 - 02/2002
4	Atherosclerotic Plaque (Atheroma) 04/2024 - 01/2019
4	Cardiovascular Diseases (Cardiovascular Disease) 04/2024 - 01/2020
4	Edema (Dropsy) 06/2015 - 07/2003
3	Fibrosis (Cirrhosis) 01/2024 - 10/2020
3	Asthma (Bronchial Asthma) 10/2020 - 12/2005
2	Necrosis 01/2024 - 01/2018
2	Heart Failure 08/2023 - 01/2020
2	COVID-19 01/2022 - 01/2020
2	Disease Progression 08/2020 - 01/2020
1	Dementia (Dementias) 01/2024
1	Cardiomegaly (Heart Hypertrophy) 01/2024
1	Cognitive Dysfunction 01/2024
1	Human Influenza (Influenza) 01/2022
1	Breast Neoplasms (Breast Cancer) 01/2022
1	Virus Diseases (Viral Diseases) 01/2022
1	Periodontitis 11/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2020
1	Glucocorticoid Receptor Deficiency 10/2020
1	Rheumatoid Arthritis 10/2020
1	Pulmonary Embolism 01/2020
1	Cytokine Release Syndrome 01/2020
1	Cardiac Arrhythmias (Arrythmia) 01/2020
1	Atrial Fibrillation 01/2020
1	Disseminated Intravascular Coagulation 01/2020
1	Myocarditis (Carditis) 01/2020
1	Ventricular Fibrillation 01/2020
1	Ventricular Tachycardia 01/2020
1	Vascular Calcification 01/2019

Drug/Important Bio-Agent (IBA)

7	CytokinesIBA 01/2024 - 02/2006
7	Apolipoproteins E (ApoE)IBA 08/2020 - 12/2009
5	CarrageenanIBA 06/2015 - 07/2003
4	Interleukin-6 (Interleukin 6)IBA 05/2024 - 01/2018
4	ChemokinesIBA 01/2024 - 04/2013
4	LipidsIBA 01/2023 - 01/2018
4	AntigensIBA 01/2020 - 07/2004
3	Biomarkers (Surrogate Marker)IBA 05/2024 - 02/2013
3	Interleukin-17 (Interleukin 17)IBA 01/2024 - 01/2020
3	Antihypertensive Agents (Antihypertensives)IBA 12/2023 - 01/2021
3	Angiotensin IIIBA 10/2020 - 01/2018
3	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 08/2020 - 11/2005
3	ApolipoproteinsIBA 01/2018 - 12/2009
3	bindaritIBA 01/2012 - 12/2009
2	pro-brain natriuretic peptide (1-76)IBA 08/2023 - 01/2020
2	LipopolysaccharidesIBA 01/2023 - 02/2006
2	GlucocorticoidsIBA 01/2022 - 10/2020
2	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 10/2020 - 05/2005
2	LDL Lipoproteins (beta Lipoproteins)IBA 08/2020 - 01/2018
2	oxidized low density lipoproteinIBA 08/2020 - 01/2018
2	InterleukinsIBA 01/2020 - 01/2018
2	LigandsIBA 01/2018 - 01/2004
2	Peptides (Polypeptides)IBA 06/2015 - 12/2010
2	Monocyte Chemoattractant ProteinsIBA 01/2012 - 11/2011
2	salicylhydroxamic acid (SHAM)IBA 05/2011 - 06/2002
2	Rosiglitazone (Avandia)FDA Link 05/2005 - 01/2004
2	PPAR-gamma AgonistsIBA 05/2005 - 01/2004
2	DNA (Deoxyribonucleic Acid)IBA 07/2003 - 06/2002
1	C-Reactive ProteinIBA 05/2024
1	Complement System Proteins (Complement)IBA 04/2024
1	SodiumIBA 01/2024
1	SaltsIBA 01/2024
1	Interleukin-10 (Interleukin 10)IBA 01/2024
1	InflammasomesIBA 01/2024
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2024
1	InterferonsIBA 01/2024
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022
1	Docetaxel (Taxotere)FDA Link 01/2022
1	Immunomodulating AgentsIBA 11/2021
1	SteroidsIBA 10/2020
1	Hydroxyproline (4 Hydroxyproline)IBA 10/2020
1	1,2-distearoylphosphatidylethanolamine (DSPE)IBA 08/2020
1	Methotrexate (Mexate)FDA LinkGeneric 08/2020
1	Lipoproteins (Lipoprotein)IBA 08/2020
1	fibrin fragment D (D-dimer)IBA 01/2020
1	Interleukin-33IBA 01/2020
1	Interleukin-22 (IL-22)IBA 01/2020
1	Creatine Kinase (Creatine Phosphokinase)IBA 01/2020
1	Dacarbazine (DIC)FDA LinkGeneric 01/2020
1	Interleukin-4 (Interleukin 4)IBA 01/2020
1	Interleukin-7 (Interleukin 7)IBA 01/2020
1	Interleukin-9 (Interleukin 9)IBA 01/2020
1	Troponin IIBA 01/2020
1	ChromatinIBA 11/2019
1	HLA-DR Antigens (HLA-DR)IBA 01/2019
1	Prostaglandins GIBA 01/2019
1	5S,12R,18R- trihydroxy- 6Z,8E,10E,14Z,16E- eicosapentaenoic acidIBA 01/2019
1	Superoxides (Superoxide)IBA 01/2019
1	Interleukin-23 (Interleukin 23)IBA 01/2018
1	CC ChemokinesIBA 01/2018
1	Extracellular Matrix ProteinsIBA 01/2018
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2018

Therapy/Procedure

6	Therapeutics 01/2023 - 01/2004
2	Stents 01/2012 - 11/2011
1	Drug Therapy (Chemotherapy) 01/2022
1	Precision Medicine 01/2021